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Article

Expression of the essential mRNA export factor Yra1p is autoregulated by a splicing-dependent mechanism.

RNA (New York, N.Y.) - 1 Aug 2002

Preker Pascal J, Kim Karen S, Guthrie Christine

Abstract excerpt

Recent evidence supports the idea that pre-mRNA splicing and mRNA export are mechanistically coupled. In metazoans, this process appears to be mediated by a multicomponent complex, which associates with the spliced RNA upstream of the exon-exon junction. One of these components (Aly/REF) has a homolog in the budding yeast Saccharomyces cerevisiae known as Yra1p. The YRA1 gene is essential for growth and required...

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Identifiers

PMID: 12212852
DOI: 10.1017/s1355838202020046
PMCID: PMC1370319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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