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Article

Transforming growth factor-beta1 negatively regulates crystallin expression in teeth.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Sept 2002

Thyagarajan Tamizchelvi, Kulkarni Ashok B

Abstract excerpt

Previously, we have reported that targeted overexpression of transforming growth factor (TGF) beta1 in the teeth of the transgenic mice (dTGF-beta1) results in a novel tooth phenotype phenomimicking the most prevalent tooth disorders in human. This phenotype was associated with discoloration and attrition of teeth due to defective mineralization. Here, we report a novel expression of crystallin family members in...

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PMID: 12211442
DOI: 10.1359/jbmr.2002.17.9.1710

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