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Article

The effect of TGF-beta 2 on dentin apposition and hardness in transgenic mice.

Advances in dental research - 1 Aug 2001

DenBesten P K, Machule D, Gallagher R, Marshall G W, Mathews C, Filvaroff E

Abstract excerpt

Transforming growth factor beta, TGF-beta, is expressed during tooth formation and can induce pre-odontoblast differentiation and formation of functional odontoblast-like cells in vitro. In addition, exogenous TGF-beta can increase reparative dentin formation, presumably by acting on odontoblasts. In this study, we examined the tooth phenotype of transgenic mice, in which TGF-beta 2 expression is directed by the...

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Source

Identifiers

PMID: 12640737
DOI: 10.1177/08959374010150010901

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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