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Article

Excessive Wnt/β-catenin signaling disturbs tooth-root formation.

Journal of periodontal research - 1 Aug 2013

Bae C H, Lee J Y, Kim T H, Baek J A, Lee J C, Yang X, Taketo M M, Jiang R, Cho E S

Abstract excerpt

BACKGROUND AND OBJECTIVE: Wingless-type MMTV integration site family (Wnt)/β-catenin signaling plays an essential role in cellular differentiation and matrix formation during skeletal development. However, little is known about its role in tooth-root formation. In a previous study, we found excessive formation of dentin and cementum in mice with constitutive β-catenin stabilization in the dental mesenchyme. In...

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Identifiers

PMID: 23050778
DOI: 10.1111/jre.12018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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