Article
Enamel and dental anomalies in latent-transforming growth factor beta-binding protein 3 mutant mice.
European journal of oral sciences - 1 Feb 2017
Morkmued Supawich, Hemmerle Joseph, Mathieu Eric, Laugel-Haushalter Virginie, Dabovic Branka, Rifkin Daniel B, Dollé Pascal, Niederreither Karen, Bloch-Zupan Agnès
Abstract excerpt
Latent-transforming growth factor beta-binding protein 3 (LTBP-3) is important for craniofacial morphogenesis and hard tissue mineralization, as it is essential for activation of transforming growth factor-β (TGF-β). To investigate the role of LTBP-3 in tooth formation we performed micro-computed tomography (micro-CT), histology, and scanning electron microscopy analyses of adult Ltbp3-/- mice. The Ltbp3-/-...
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