Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcription Factor FoxO1 Is Essential for Enamel Biomineralization

24 Jan 2012

Abstract excerpt

The Transforming growth factor β (Tgf-β) pathway, by signaling via the activation of Smad transcription factors, induces the expression of many diverse downstream target genes thereby regulating a vast array of cellular events essential for proper development and homeostasis. In order for a specific cell type to properly interpret the Tgf-β signal and elicit a specific cellular response, cell-specific...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone and Dental Protein Studies
Share to dental development and anomalies
Share to Periodontal Regeneration and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22291941
DOI: 10.1371/journal.pone.0030357

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcription Factor FoxO1 Is Essential for Enamel BiomineralizationPMID 22291941Read ↗

FoxO6 regulates Hippo signaling and growth of the craniofacial complexSemantic proximity Read ↗

MACF1 Deficiency Suppresses Tooth Mineralization through IGF1 mediated Crosstalk Between Odontoblasts and AmeloblastsSemantic proximity Read ↗

A FoxO-Smad synexpression group in human keratinocytes.Semantic proximity Read ↗

FOXO3 and Related Transcription Factors in Development, Aging, and Exceptional LongevitySemantic proximity Read ↗

The Role of FoxOs in Bone Health and Disease.Semantic proximity Read ↗

FoxO1 is a positive regulator of bone formation by favoring protein synthesis and resistance to oxidative stress in osteoblasts.Semantic proximity Read ↗

Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells.Semantic proximity Read ↗

FOXO1 and FOXO3 transcription factors have unique functions in meniscus development and homeostasis during aging and osteoarthritisSemantic proximity Read ↗

FOXOs attenuate bone formation by suppressing Wnt signaling.Semantic proximity Read ↗

FOXO1 regulates RUNX2 ubiquitination through SMURF2 in calcific aortic valve diseaseSemantic proximity Read ↗

Transgenic mice expressing a ligand-inducible cre recombinase in osteoblasts and odontoblasts: a new tool to examine physiology and disease of postnatal bone and tooth.Semantic proximity Read ↗

Mutations in the latent TGF-beta binding protein 3 (LTBP3) gene cause brachyolmia with amelogenesis imperfectaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.