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Article

Dspp-independent Effects of Transgenic Trps1 Overexpression on Dentin Formation.

Journal of dental research - 1 Aug 2015

Mobley C G, Kuzynski M, Zhang H, Jani P, Qin C, Napierala D

Abstract excerpt

The Trps1 transcription factor is highly expressed in dental mesenchyme and preodontoblasts, while in mature, secretory odontoblasts, it is expressed at low levels. Previously, we have shown that high Trps1 levels in mature odontoblasts impair their function in vitro and in vivo. Col1a1-Trps1 transgenic (Trps1-Tg) mice demonstrate defective dentin secretion and mineralization, which are associated with...

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Identifiers

PMID: 25999324
DOI: 10.1177/0022034515586709
PMCID: PMC4530388

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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