TGF-beta1 is essential for the homeostasis of the dentin-pulp complex.

doi:10.1111/j.1600-0722.1998.tb02174.x

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Article

TGF-beta1 is essential for the homeostasis of the dentin-pulp complex.

European journal of oral sciences - 1 Jan 1998

D'Souza R N, Cavender A, Dickinson D, Roberts A, Letterio J

Abstract excerpt

Among the complex network of cytokines that influence odontoblast function during development and repair, TGF-beta1 is unique in its dual abilities to function as a potent immunosuppressant and as an inducer of extracellular matrix production. These properties underscore the importance of this mo...

Topics

Animals
Anti-Inflammatory Agents
Crosses, Genetic
DNA-Binding Proteins
Dental Pulp
Dentin
Dexamethasone
Female
Homeostasis
Immunologic Deficiency Syndromes
Male
Mice
Mice, Knockout
Odontogenesis
Phenotype
Transforming Growth Factor beta

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