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Article

Analysis of tooth development in mice bearing a TGF-beta 1 null mutation.

Connective tissue research - 1 Jan 1995

D'Souza R N, Litz M

Abstract excerpt

While transforming growth factor-beta 1 (TGF-beta 1) and its related mammalian isoforms TGF-beta 2 and TGF-beta 3 are coexpressed in developing tooth organs, the specific biological role of each isoform is unknown. To delineate the role of TGF-beta 1 in odontogenesis, we have studied tissues from mice that lack a functional TGF-beta 1 gene. Histologic analyses revealed that in TGF-beta 1 (-/-) mice, tooth...

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Identifiers

PMID: 7554934
DOI: 10.3109/03008209509013704

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of tooth development in mice bearing a TGF-beta 1 null mutation.PMID 7554934Read ↗

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