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Article

Analysis of tooth development in mice bearing a TGF-beta 1 null mutation.

Connective tissue research - 1 Jan 1995

D'Souza R N, Litz M

Abstract excerpt

While transforming growth factor-beta 1 (TGF-beta 1) and its related mammalian isoforms TGF-beta 2 and TGF-beta 3 are coexpressed in developing tooth organs, the specific biological role of each isoform is unknown. To delineate the role of TGF-beta 1 in odontogenesis, we have studied tissues from...

Topics

Animals
Antibodies
Cell Differentiation
Dental Papilla
Enamel Organ
Gene Expression Regulation, Developmental
Genotype
Heterozygote
Homozygote
In Situ Hybridization
Mice
Mice, Knockout
Morphogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Odontogenesis

RNA, Messenger

Tooth Germ

Transforming Growth Factor beta

Source

Identifiers

PMID: 7554934
DOI: 10.3109/03008209509013704

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7554934-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Analysis of tooth development in mice bearing a TGF-beta 1 null mutation.PMID 7554934Read ↗

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Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development.Semantic proximity Read ↗

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Inhibition of transforming growth factor-beta type II receptor signaling accelerates tooth formation in mouse first branchial arch explants.Semantic proximity Read ↗

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