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Article

Further evidence for an association of the paraoxonase 1 (PON1) Met-54 allele with Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society - 1 Jul 2002

Carmine Andrea, Buervenich Silvia, Sydow Olof, Anvret Maria, Olson Lars

Abstract excerpt

Paraoxonase1 (PON1) is an arylesterase mainly expressed in the liver that hydrolyzes organophosphates such as pesticides, reported risk factors for Parkinson's disease (PD), and other neurotoxins. A Leu-Met 54 polymorphism in the gene for PON1-affecting enzyme activity was recently shown, employing a new restriction enzyme technique, to be associated with Parkinson's disease. We examined the same polymorphism by...

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Source

Identifiers

PMID: 12210872
DOI: 10.1002/mds.10172

Genes

PON1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Further evidence for an association of the paraoxonase 1 (PON1) Met-54 allele with Parkinson's disease.PMID 12210872Read ↗

Association of a protective paraoxonase 1 (PON1) polymorphism in Parkinson's disease.Semantic proximity Read ↗

Paraoxonase 1 Met--Leu 54 polymorphism is associated with Parkinson's disease.Semantic proximity Read ↗

Association of Paraoxonse1 (PON1) Genotypes with the Activity of PON1 in Patients with Parkinson's Disease.Semantic proximity Read ↗

Role of PON1 L55M Gene Polymorphism in Parkinson's Disease among North Indian Population.Semantic proximity Read ↗

Paraoxonase 1 (PON1) gene polymorphisms and Parkinson's disease in a Finnish population.Semantic proximity Read ↗

Role of paraoxonase 1 (PON1) in organophosphate metabolism: implications in neurodegenerative diseases.Semantic proximity Read ↗

Effects of 5' regulatory-region polymorphisms on paraoxonase-gene (PON1) expression.Semantic proximity Read ↗

Polymorphism in the P-glycoprotein drug transporter MDR1 gene: a possible link between environmental and genetic factors in Parkinson's disease.Semantic proximity Read ↗

Paraoxonase 1, agricultural organophosphate exposure, and Parkinson disease.Semantic proximity Read ↗

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Polymorphism in the P-glycoprotein drug transporter MDR1 geneSemantic proximity Read ↗

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