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Article

Association of Paraoxonse1 (PON1) Genotypes with the Activity of PON1 in Patients with Parkinson's Disease.

Acta neurologica Taiwanica - 15 Sept 2019

Mota Ali, Hemati-Dinarvand Mohsen, Akbar Taheraghdam Ali, Reza Nejabati Hamid, Ahmadi Ravan, Ghasemnejad Tohid, Hasanpour Milad, Valilo Mohammad

Abstract excerpt

OBJECTIVE: Various numbers of factors such as oxidative stress, neurotoxins, and pesticides have been implicated in its pathophysiology of Parkinson's disease (PD). Paraoxonas1 (PON1) metabolizes xenobiotics, including pesticides. Therefore, we surveyed the relationship between PON1 polymorphisms with its activities in the pathogenesis of Parkinson's disease.. METHODS: We investigated polymorphisms of the PON1...

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PMID: 32002976

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