Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Paraoxonase 1 Met--Leu 54 polymorphism is associated with Parkinson's disease.

Journal of the neurological sciences - 1 Mar 2001

Akhmedova S N, Yakimovsky A K, Schwartz E I

Abstract excerpt

Two up-to-date known paraoxonase 1 (PON1) polymorphisms (Gln--Arg 191 and Leu--Met 54) affect the hydrolysis of toxic oxons and might intensify effects of pollutants, organophosphates and other environmental chemicals in development of Parkinson's disease (PD). We reported previously that PON1 G1n--Arg 191 polymorphism did not influence on the susceptibility to PD. In the present study we have investigated the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Aryldialkylphosphatase
Share to Chi-Square Distribution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Esterases

Share to Gene Frequency

Share to Odds Ratio

Share to Parkinson Disease

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 11239953
DOI: 10.1016/s0022-510x(01)00439-7

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Paraoxonase 1 Met--Leu 54 polymorphism is associated with Parkinson's disease.PMID 11239953Read ↗

Gln --> Arg 191 polymorphism of paraoxonase and Parkinson's disease.Semantic proximity Read ↗

Further evidence for an association of the paraoxonase 1 (PON1) Met-54 allele with Parkinson's disease.Semantic proximity Read ↗

Paraoxonase 1 (PON1) gene polymorphisms and Parkinson's disease in a Finnish population.Semantic proximity Read ↗

Association of paraoxonase 1 gene polymorphisms with risk of Parkinson's disease: a meta-analysis.Semantic proximity Read ↗

Association of a protective paraoxonase 1 (PON1) polymorphism in Parkinson's disease.Semantic proximity Read ↗

Association of Paraoxonse1 (PON1) Genotypes with the Activity of PON1 in Patients with Parkinson's Disease.Semantic proximity Read ↗

Role of PON1 L55M Gene Polymorphism in Parkinson's Disease among North Indian Population.Semantic proximity Read ↗

Genetic polymorphism of paraoxonase 1 (PON1) and susceptibility to Parkinson's disease.Semantic proximity Read ↗

Paraoxonase 1 polymorphisms L55M and Q192R were not risk factors for Parkinson's disease: a HuGE review and meta-analysis.Semantic proximity Read ↗

Role of paraoxonase 1 (PON1) in organophosphate metabolism: implications in neurodegenerative diseases.Semantic proximity Read ↗

Paraoxonase 1 (PON1) polymorphisms and risk for essential tremor.Semantic proximity Read ↗

Paraoxonase 1 in neurological disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.