Association between paraoxonase-1 gene polymorphisms and risk of metabolic syndrome.

Abstract excerpt

Paraoxonase-1 (PON1), a high-density lipoprotein (HDL) associated enzyme, is involved in the metabolism and detoxification of insecticides and pesticides. Three polymorphisms within the PON1 gene affect the enzyme activity. Two of these (L55M and Q192R) are located at the coding region and the third (-107C/T) is in promoter region. We performed a case-control study in order to elucidate the possible contribution...

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• Aryldialkylphosphatase
• Case-Control Studies
• DNA Primers
• Iran
• Metabolic Syndrome