Article
Interactions between Ras1, dMyc, and dPI3K signaling in the developing Drosophila wing.
Genes & development - 1 Sept 2002
Prober David A, Edgar Bruce A
Abstract excerpt
The Ras GTPase links extracellular signals to intracellular mechanisms that control cell growth, the cell cycle, and cell identity. An activated form of Drosophila Ras (Ras(V12)) promotes these processes in the developing wing, but the effector pathways involved are unclear. Here, we present evidence indicating that Ras(V12) promotes cell growth and G(1)/S progression by increasing dMyc protein levels and...
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