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Article

Allelic variation in the human prodynorphin gene promoter and schizophrenia.

Neuropsychobiology - 1 Jan 2002

Ventriglia M, Bocchio Chiavetto L, Bonvicini C, Tura G B, Bignotti S, Racagni G, Gennarelli M

Abstract excerpt

Experimental and clinical studies suggest an involvement of the opioid neuropeptide system in schizophrenia. In particular, the prodynorphin (PDYN), the precursor of the dynorphin opioid peptides, has been shown to play an important role in several aspects of human mental diseases. Recently, a fu...

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Source

Identifiers

PMID: 12207142
DOI: 10.1159/000063571

Genes

PDYN
DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12207142-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Allelic variation in the human prodynorphin gene promoter and schizophrenia.PMID 12207142Read ↗

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Potentially functional polymorphism in the promoter region of prodynorphin gene may be associated with protection against cocaine dependence or abuse.Semantic proximity Read ↗

An allelic variation in the human prodynorphin gene promoter alters stimulus-induced expression.Semantic proximity Read ↗

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