Article
Dopamine D3 receptor Gly9/Ser9 polymorphism and schizophrenia: no increased frequency of homozygosity in German familial cases.
Schizophrenia research - 1 May 1996
Rietschel M, Nöthen M M, Albus M, Maier W, Minges J, Bondy B, Körner J, Hemmer S, Fimmers R, Möller H J, Wildenauer D, Propping P
Abstract excerpt
Disturbances in the dopaminergic transmission have been implicated in the etiology of schizophrenia. Recently, an association of schizophrenia with increased homozygosity of a Gly9/Ser9 polymorphism in the dopamine D3 receptor gene (DRD3) has been reported (Crocq et al., 1992; Mant et al., 1994)....
Topics
- Adult
- Alleles
- Codon, Terminator
- DNA Mutational Analysis
- Female
- Gene Frequency
- Germany
- Glycine
- Homozygote
- Humans
- Male
- Middle Aged
- Polymorphism, Genetic
- Psychiatric Status Rating Scales
- Receptors, Dopamine D2