Article
A cluster of single nucleotide polymorphisms in the 5'-leader of the human dopamine D3 receptor gene (DRD3) and its relationship to schizophrenia.
Neuroscience letters - 21 Jan 2000
Sivagnanasundaram S, Morris A G, Gaitonde E J, McKenna P J, Mollon J D, Hunt D M
Abstract excerpt
The association between schizophrenia and the Ser9Gly variant of the dopamine D3 receptor gene (DRD3) has been the subject of numerous studies. Under meta-analysis this site, or one or more in linkage disequilibrium with it, appears to contribute a small increase to the relative risk of schizophrenia. In this study, 768 bp of the 5'-leader region of DRD3 mRNA was screened for polymorphisms to assess their...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
