Article
No association between the Ser9Gly polymorphism of the dopamine D3 receptor gene and schizophrenia in a Spanish sample.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2007
Lorenzo C Vaquero, Baca-Garcia E, Hernandez M Diaz, Martin C Botillo, Perez-Rodriguez M M, Saiz-Gonzalez M D, Fernández P, Gutierrez F J Quintero, Saiz-Ruiz J, Piqueras J Fernandez, de Rivera J L Gonzalez, de Leon J
Abstract excerpt
This study aims to further evaluate the controversial association between the Ser9Gly polymorphism in codon 9 of the D3 dopamine receptor gene (DRD3) and schizophrenia in psychiatric inpatients acutely hospitalized in two general hospitals in Madrid, Spain. The Ser9Gly polymorphism of the DRD3 was examined in 178 schizophrenic patients, 286 patients with other psychiatric diagnoses, and 132 controls recruited....
Topics
- Case-Control Studies
- Gene Frequency
- Genetic Linkage
- Genotype
- Glycine
- Humans
- Polymorphism, Single Nucleotide
- Receptors, Dopamine D3
- Schizophrenia