Article
Polymorphism of Prodynorphin promoter is associated with schizophrenia in Chinese population.
Acta pharmacologica Sinica - 1 Aug 2004
Zhang Chang-Shun, Tan Zheng, Lu Lan, Wu Sheng-Nan, He Ying, Gu Niu-Fan, Feng Guo-Yin, He Lin
Abstract excerpt
AIM: To investigate the correlation between single nucleotide polymorphisms (SNPs) of functional candidate gene Prodynorphin (PDYN) and schizophrenia. METHODS: SNPs in the promoter and exon regions of PDYN were screened and genotyped for association study in a cohort of Chinese Han schizophrenia cases and controls. RESULTS: Two SNPs PDYN-1576C>T and PDYN-946C>G were identified in the promoter region but...
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