Article
No association between the DRD3 Ser9Gly polymorphism and schizophrenia.
Schizophrenia research - 1 Jan 2008
Fathalli Ferid, Rouleau Guy A, Xiong Lan, Tabbane Karim, Benkelfat Chawki, Deguzman Rosherrie, Zoltan Danics, Lal Samarthji, D'cruz Sarogini, Joober Ridha
Abstract excerpt
OBJECTIVE: To investigate the association between a Ser9Gly polymorphism of the dopamine D3 receptor gene (DRD3) and schizophrenia. METHODS: 408 schizophrenic patients and 172 control subjects were compared with regard to their DRD3 Ser9Gly genotypic and allelic frequencies. In addition, we carried out a family-based association study including 183 pedigrees (472 subjects) using the transmission disequilibrium...
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