Article
An allelic variation in the human prodynorphin gene promoter alters stimulus-induced expression.
Journal of neurochemistry - 1 Feb 2000
Zimprich A, Kraus J, Wöltje M, Mayer P, Rauch E, Höllt V
Abstract excerpt
Prodynorphin, the precursor of the dynorphin opioid peptides, has been shown to play an important role in several aspects of human diseases and complex traits, e.g., drug abuse, epilepsy, and mood disorders. The objective of this study was to identify polymorphisms in the 5' control region of the...
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