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Article

Transcription factors Nkx3.1 and Nkx3.2 (Bapx1) play an overlapping role in sclerotomal development of the mouse.

Mechanisms of development - 1 Sept 2002

Herbrand Heike, Pabst Oliver, Hill Robert, Arnold Hans-Henning

Abstract excerpt

The homeobox containing transcription factors Nkx3.1 and Nkx3.2 (Bapx1) are transiently coexpressed in somites during early embryonic mouse development. Targeted disruption of the Nkx3.2 (Bapx1) gene in mice results in limited defects of chondrocranial bones and the axial skeleton, particularly pronounced in cervical vertebrae. In contrast, inactivation of the Nkx3.1 gene causes no apparent skeletal phenotype...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12204261
DOI: 10.1016/s0925-4773(02)00207-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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