Article
The role of the notochord for epaxial myotome formation in the mouse.
Cellular and molecular biology (Noisy-le-Grand, France) - 1 Jul 1999
Dietrich S, Schubert F R, Gruss P, Lumsden A
Abstract excerpt
The vertebrate somite is the source of all trunk skeletal muscles. Myogenesis in avian embryos is thought to depend on signals from notochord and neural tube for the epaxial muscles, and signals from lateral mesoderm and surface ectoderm for the hypaxial muscles. However, this hypothesis has to be tested because in mouse mutants lacking a notochord the presence of a fused myotome beneath the neural tube has been...
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