Article
The role of Bapx1 (Nkx3.2) in the development and evolution of the axial skeleton.
Journal of anatomy - 1 Jan 2000
Lettice L, Hecksher-Sørensen J, Hill R
Abstract excerpt
The bagpipe-related homeobox-containing genes are members of the NK family, bagpipe (bap) was first identified in Drosophila and there are three different bagpipe-related genes in vertebrates. Only two of these are found in mammals, the Nkx3.1 and the Bapxl (Nkx3.2) gene. The targeted mutation in the mouse Bapxl gene shows a vertebral phenotype in which the ventromedial elements are lacking; these are the centra...
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