Article
Pax1 and Pax9 synergistically regulate vertebral column development.
Development (Cambridge, England) - 1 Dec 1999
Peters H, Wilm B, Sakai N, Imai K, Maas R, Balling R
Abstract excerpt
The paralogous genes Pax1 and Pax9 constitute one group within the vertebrate Pax gene family. They encode closely related transcription factors and are expressed in similar patterns during mouse embryogenesis, suggesting that Pax1 and Pax9 act in similar developmental pathways. We have recently shown that mice homozygous for a defined Pax1 null allele exhibit morphological abnormalities of the axial skeleton,...
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