Article
Targeted disruption of the homeobox gene Nkx2.9 reveals a role in development of the spinal accessory nerve.
Development (Cambridge, England) - 1 Mar 2003
Pabst Oliver, Rummelies Janin, Winter Barbara, Arnold Hans-Henning
Abstract excerpt
The homeodomain-containing transcription factor Nkx2.9 is expressed in the ventralmost neural progenitor domain of the neural tube together with the related protein Nkx2.2 during early mouse embryogenesis. Cells within this region give rise to V3 interneurons and visceral motoneurons in spinal cord and hindbrain, respectively. To investigate the role of the Nkx2.9 gene, we generated a mutant mouse by targeted...
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