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<i>nkx3.2</i> mutant zebrafish accommodate jaw joint loss through a phenocopy of the head shapes of Paleozoic jawless fish

2019-09-19

Abstract excerpt

The vertebrate jaw is a versatile feeding apparatus that facilitated explosive diversification. To function, it requires a joint between the upper and lower jaws, so jaw joint defects - such as osteoarthritis or even ankylosis - are often highly disruptive and difficult to study. To describe consequences of jaw-joint dysfunction, we engineered two independent null alleles of a single jaw-joint marker gene, nkx3.2...

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Literature Corpus work
255d299e-1c91-593f-8c11-92532c27ba07
DOI
10.1101/776351
Open publication

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<i>nkx3.2</i> mutant zebrafish accommodate jaw joint loss through a phenocopy of the head shapes of Paleozoic jawless fishDOI 10.1101/776351
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