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Article

The role of Pax-1 in axial skeleton development.

Development (Cambridge, England) - 1 May 1994

Wallin J, Wilting J, Koseki H, Fritsch R, Christ B, Balling R

Abstract excerpt

Previous studies have identified a single amino-acid substitution in the transcriptional regulator Pax-1 as the cause of the mouse skeletal mutant undulated (un). To evaluate the role of Pax-1 in the formation of the axial skeleton we have studied Pax-1 protein expression in early sclerotome cells and during subsequent embryonic development, and we have characterized the phenotype of three different Pax-1 mouse...

Topics

Animals
Base Sequence
Cell Differentiation
DNA Primers
DNA-Binding Proteins
Gene Expression
Genotype
Immunohistochemistry
Mesoderm
Mice
Mice, Mutant Strains
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Notochord

Paired Box Transcription Factors

Phenotype

Spine

Transcription Factors

Source

Identifiers

PMID: 8026324
DOI: 10.1242/dev.120.5.1109

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8026324-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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