Article
The role of Pax-1 in axial skeleton development.
Development (Cambridge, England) - 1 May 1994
Wallin J, Wilting J, Koseki H, Fritsch R, Christ B, Balling R
Abstract excerpt
Previous studies have identified a single amino-acid substitution in the transcriptional regulator Pax-1 as the cause of the mouse skeletal mutant undulated (un). To evaluate the role of Pax-1 in the formation of the axial skeleton we have studied Pax-1 protein expression in early sclerotome cells and during subsequent embryonic development, and we have characterized the phenotype of three different Pax-1 mouse...
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