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Article

Emerging concepts in colorectal neoplasia.

Gastroenterology - 1 Sept 2002

Jass Jeremy R, Whitehall Vicki L J, Young Joanne, Leggett Barbara A

Abstract excerpt

An understanding of the mechanisms that explain the initiation and early evolution of colorectal cancer should facilitate the development of new approaches to effective prevention and intervention. This review highlights deficiencies in the current model for colorectal neoplasia in which APC mutation is placed at the point of initiation. Other genes implicated in the regulation of apoptosis and DNA repair may...

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Share to Intestinal Polyps
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12198712
DOI: 10.1053/gast.2002.35392

Genes

MGMT
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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