Article
Role of the serrated pathway in colorectal cancer pathogenesis.
Gastroenterology - 1 Jun 2010
Leggett Barbara, Whitehall Vicki
Abstract excerpt
The "serrated neoplastic pathway" describes the progression of serrated polyps, including sessile serrated adenomas and traditional serrated adenomas, to colorectal cancer. The recognition of this pathway during the last 15 years has led to a paradigm shift in our understanding of the molecular basis of colorectal cancer and significant changes in clinical practice. These findings are particularly relevant to...
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