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Article

Serrated and Non-Serrated Precursor Lesions of Colorectal Cancer

17 Dec 2014

Abstract excerpt

Although often viewed as a single disease, colorectal cancer more accurately represents a family of diseases with different precursor lesions. Conventional (tubular, tubulovillous and villous) adenomas are the most common neoplastic lesions occurring in the large intestine. They have adenomatous polyposis coli (APC) mutations and arise from dysplastic aberrant crypt foci, initially as polyclonal lesions. In...

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PMID: 25531494
DOI: 10.1159/000366032

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