Article
Colorectal serrated adenocarcinoma.
Histopathology - 1 Jan 2007
Mäkinen M J
Abstract excerpt
Colorectal cancer (CRC) ranks among the three most common cancers in terms of both cancer incidence and cancer-related deaths in most Western countries. Serrated adenocarcinoma is a recently described, distinct variant of CRC, accounting for about 7.5% of all CRCs and up to 17.5% of most proximal CRCs. It has been postulated that about 10-15% of sporadic CRCs would have their origin in serrated polyps that...
Topics
- Adaptor Proteins, Signal Transducing
- Adenocarcinoma
- Adenoma
- Carrier Proteins
- Colonic Polyps
- Colorectal Neoplasms
- CpG Islands
- DNA Methylation
- DNA Modification Methylases
- DNA Repair Enzymes
- Humans
- Microsatellite Instability
- MutL Protein Homolog 1
- Mutation
- Nuclear Proteins
- Precancerous Conditions
- Proto-Oncogene Proteins B-raf
- Tumor Suppressor Protein p14ARF