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Article

Emerging pathways in colorectal-cancer development.

The Lancet. Oncology - 1 Feb 2002

Haydon Andrew M M, Jass Jeremy R

Abstract excerpt

The past decade has seen the emergence of new pathways in the development of colorectal cancer. There is now clear evidence that subsets of these tumours do not show chromosomal instability and do not follow the suppressor pathway. Instead, about 15% of colorectal cancers are characterised by microsatellite instability (MSI). This feature arises through defective DNA mismatch repair, which is related either to a...

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Identifiers

PMID: 11905459
DOI: 10.1016/s1470-2045(02)00649-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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