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Article

Spatial memory dissociations in mice lacking GluR1.

Nature neuroscience - 1 Sept 2002

Reisel D, Bannerman D M, Schmitt W B, Deacon R M J, Flint J, Borchardt T, Seeburg P H, Rawlins J N P

Abstract excerpt

Gene-targeted mice lacking the AMPA receptor subunit GluR1 (GluR-A) have deficits in hippocampal CA3-CA1 long-term potentiation. We now report that they showed normal spatial reference learning and memory, both on the hidden platform watermaze task and on an appetitively motivated Y-maze task. In contrast, they showed a specific spatial working memory impairment during tests of non-matching to place on both the...

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Source

Identifiers

PMID: 12195431
DOI: 10.1038/nn910

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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