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Article

Enhanced odor discrimination and impaired olfactory memory by spatially controlled switch of AMPA receptors.

PLoS biology - 1 Nov 2005

Shimshek Derya R, Bus Thorsten, Kim Jinhyun, Mihaljevic Andre, Mack Volker, Seeburg Peter H, Sprengel Rolf, Schaefer Andreas T

Abstract excerpt

Genetic perturbations of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors (AMPARs) are widely used to dissect molecular mechanisms of sensory coding, learning, and memory. In this study, we investigated the role of Ca2+-permeable AMPARs in olfactory behavior. AMPAR modification was obtained by depletion of the GluR-B subunit or expression of unedited GluR-B(Q), both leading to increased Ca2+...

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Source

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Identifiers

PMID: 16216087
DOI: 10.1371/journal.pbio.0030354
PMCID: PMC1255741

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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