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Article

Working memory deficits in retinoid X receptor gamma-deficient mice.

Learning & memory (Cold Spring Harbor, N.Y.) - 1 Jan 2000

Wietrzych Marta, Meziane Hamid, Sutter Anne, Ghyselinck Norbert, Chapman Paul F, Chambon Pierre, Krezel Wojciech

Abstract excerpt

Retinoid signaling has been recently shown to be required for mnemonic functions in rodents. To dissect the behavioral and molecular mechanisms involved in this requirement, we have analyzed the spatial and recognition working memory in mice carrying null mutations of retinoid receptors RARbeta and RXRgamma. Double mutants appeared deficient in spatial working memory as tested in spontaneous alternation in the...

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Identifiers

PMID: 15897255
DOI: 10.1101/lm.89805
PMCID: PMC1142461

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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