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Article

Identification of rat quantitative trait loci that regulate LPS-induced pro-inflammatory cytokine responses.

Scandinavian journal of immunology - 1 Sept 2002

Xu H, Wallstrom E, Becanovic K, Dahlman I, Lorentzen J C

Abstract excerpt

Bacterial lipopolysaccharides (LPSs) trigger innate immune effector functions, such as the production of pro-inflammatory cytokines. Here we utilized major histocompatibility complex (MHC)-congenic rats to dissect the genetic basis of strain-dependent variations of LPS-induced tumour necrosis factor-alpha (TNF-alpha) levels in a whole blood in vitro assay. PVG.1AV1 background was associated with a high response,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12193225
DOI: 10.1046/j.1365-3083.2002.01130.x

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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