Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel Regulators of the Systemic Response to Lipopolysaccharide

4 Dec 2010

Abstract excerpt

Our understanding of the role that host genetic factors play in the initiation and severity of infections caused by gram-negative bacteria is incomplete. To identify novel regulators of the host response to lipopolysaccharide (LPS), 11 inbred murine strains were challenged with LPS systemically. In addition to two strains lacking functional TLR4 (C3H/HeJ and C57BL/6J(TLR4-/-)), three murine strains with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Response and Inflammation
Share to Neonatal Respiratory Health Research
Share to NF-κB Signaling Pathways

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21131441
DOI: 10.1165/rcmb.2010-0342oc

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel Regulators of the Systemic Response to LipopolysaccharidePMID 21131441Read ↗

Identification of novel genes that mediate innate immunity using inbred mice.Semantic proximity Read ↗

The genetics of innate immunity.Semantic proximity Read ↗

Genes other than TLR4 are involved in the response to inhaled LPS.Semantic proximity Read ↗

Genetic control of the innate immune response.Semantic proximity Read ↗

Transcriptional response in a sepsis mouse model reflects transcriptional response in sepsis patientsSemantic proximity Read ↗

Transcriptional Response in a Sepsis Mouse Model Reflects Transcriptional Response in Sepsis PatientsSemantic proximity Read ↗

Presence of Lps(d) mutation influences cytokine regulation in vivo by the Mycoplasma arthritidis mitogen superantigen and lethal toxicity in mice infected with M. arthritidis.Semantic proximity Read ↗

Genetic determinants influencing the response to injury, inflammation, and sepsis.Semantic proximity Read ↗

Genetic regulation of endotoxin-induced airway disease.Semantic proximity Read ↗

Tlr4: central component of the sole mammalian LPS sensor.Semantic proximity Read ↗

GENETIC COMPONENT IN THE INFLAMMATORY RESPONSE INDUCED BY BACTERIAL LIPOPOLYSACCHARIDESemantic proximity Read ↗

Quantitative trait loci modulate neutrophil infiltration in the liver during LPS-induced inflammation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.