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Article

Genetic regulation of endotoxin-induced airway disease.

Genomics - 1 Jun 2004

Cook Donald N, Wang Shuibang, Wang Yonghong, Howles Gabriel P, Whitehead Gregory S, Berman Katherine G, Church Tony D, Frank Bryan C, Gaspard Renee M, Yu Yan, Quackenbush John, Schwartz David A

Abstract excerpt

To identify novel genes regulating the biologic response to lipopolysaccharide (LPS), we used a combination of quantitative trait locus (QTL) analysis and microarray-based gene expression studies of C57BL/6J x DBA/2J(BXD) F2 and recombinant inbred (RI) mice. A QTL affecting pulmonary TNF-alpha production was identified on chromosome 2, and a region affecting both polymorphonuclear leukocyte recruitment and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15177550
DOI: 10.1016/j.ygeno.2003.12.008

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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