Article
Mapping lipopolysaccharide response loci in mice using recombinant inbred and congenic strains.
Genomics - 15 Nov 1999
Matesic L E, De Maio A, Reeves R H
Abstract excerpt
Lipopolysaccharide (LPS) induces proliferation of splenic B-cells, and this response was found to be significantly lower in A/J than in C57BL/6J (B6) mice. Several strains and substrains mirrored the high and low responses of B6 and A/J. Assessment of 26 AXB/BXA recombinant inbred (RI) mouse strains identified 23 strains with a low (A/J-like), high (B6-like), or intermediate response. The three remaining RI...
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