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Article

Genome-Wide Association Study of Genetic Variants in LPS-Stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α Cytokine Response in a Danish Cohort.

PloS one - 1 Jan 2013

Larsen Margit Hørup, Albrechtsen Anders, Thørner Lise Wegner, Werge Thomas, Hansen Thomas, Gether Ulrik, Haastrup Eva, Ullum Henrik

Abstract excerpt

BACKGROUND: Cytokine response plays a vital role in various human lipopolysaccharide (LPS) infectious and inflammatory diseases. This study aimed to find genetic variants that might affect the levels of LPS-induced interleukin (IL)-6, IL-8, IL-10, IL-1ra and tumor necrosis factor (TNF)-α cytokine production. METHODS: We performed an initial genome-wide association study using Affymetrix Human Mapping 500 K...

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PMID: 23823136
DOI: 10.1371/journal.pone.0066262
PMCID: PMC3688878

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TNF

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Source receipt: pubmed, retrieved 7 Sept 2026.

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