Article
Analysis of the inducible nitric oxide synthase gene polymorphisms in Czech patients with atopic diseases.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Dec 2006
Holla L I, Stejskalova A, Znojil V, Vasku A
Abstract excerpt
BACKGROUND: Nitric oxide (NO) is an important mediator of physiologic processes in the airways; it plays a significant role in the regulation of the T helper type 1/type 2 balance and contributes to the development of atopic diseases. OBJECTIVE: We analysed several polymorphisms mainly in the promoter region of the inducible NO synthase (NOS2, iNOS) gene and investigated their associations with asthma and/or...
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