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Article

C-kit mutations in gastrointestinal stromal tumours.

Pathology - 1 Aug 2002

Morey Adrienne L, Wanigesekera G David, Hawkins Nicholas J, Ward Robyn L

Abstract excerpt

AIMS: Gastrointestinal stromal tumours (GISTs), once assumed to be of smooth muscle origin, generally express CD117 and CD34, similar to the interstitial cells of Cajal. Assessment of malignant potential in GISTs is problematic, especially on small biopsies. Some recent data indicate that mutations in the juxtamembrane domain (exon 11) of the c-kit (CD117) proto-oncogene may be associated with a worse prognosis....

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Identifiers

PMID: 12190287
DOI: 10.1080/00313020220147122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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C-kit mutations in gastrointestinal stromal tumours.PMID 12190287Read ↗

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[Analysis of c-kit gene mutations in gastrointestinal stromal tumors].Semantic proximity Read ↗

KIT exon 11 codon 557/558 deletion/insertion mutations define a subset of gastrointestinal stromal tumors with malignant potential.Semantic proximity Read ↗

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