Article
KIT exon 11 codon 557/558 deletion/insertion mutations define a subset of gastrointestinal stromal tumors with malignant potential.
World journal of gastroenterology - 28 Mar 2008
Kontogianni-Katsarou Katerina, Dimitriadis Euthimios, Lariou Constantina, Kairi-Vassilatou Evi, Pandis Nikolaos, Kondi-Paphiti Agatha
Abstract excerpt
AIM: To study the association of the frequency and pattern of KIT and PDGFRA mutations and clinicopathological factors in a group of patients with gastrointestinal stromal tumors (GIST). METHODS: Thirty patients with GIST were examined. Exons 9, 11, 13, and 17 of the KIT and exons 12 and 18 of the PDGFRA gene were analyzed for the presence of mutations by PCR amplification and direct sequencing. RESULTS: KIT or...
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