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Article

C-kit gene abnormalities in gastrointestinal stromal tumors (tumors of interstitial cells of Cajal.

Japanese journal of cancer research : Gann - 1 Dec 1999

Sakurai S, Fukasawa T, Chong J M, Tanaka A, Fukayama M

Abstract excerpt

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the GI tract, and expresses KIT and CD34 in most cases. Gain-of-function mutation of the c-kit proto-oncogene has been described, but its significance in GIST has not yet been fully evaluated. Mutation in exon 11 of the c-kit gene was determined by both polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP)...

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Source

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Identifiers

PMID: 10665649
DOI: 10.1111/j.1349-7006.1999.tb00715.x
PMCID: PMC5926026

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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