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Article

Gastrointestinal stromal tumours (GISTs) negative for KIT (CD117 antigen) immunoreactivity.

The Journal of pathology - 1 Apr 2004

Debiec-Rychter Maria, Wasag Bartosz, Stul Michel, De Wever Ivo, Van Oosterom Allan, Hagemeijer Anne, Sciot Raf

Abstract excerpt

Gastrointestinal stromal tumours (GISTs) are currently defined as mesenchymal tumours of the gastrointestinal tract that express KIT receptor tyrosine kinase. However, a small subgroup of tumours that fulfil the clinical and morphological criteria for GISTs lack KIT expression. So far, the biological features of these tumours have rarely been addressed. The present study describes seven gastrointestinal stromal...

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Source

Identifiers

PMID: 15095270
DOI: 10.1002/path.1546

Genes

KIT
PDGFRA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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