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Article

C-kit gene mutation in human gastrointestinal stromal tumors.

World journal of gastroenterology - 1 May 2004

Hou Ying-Yong, Tan Yun-Shan, Sun Meng-Hong, Wei Yong-Kun, Xu Jian-Fang, Lu Shao-Hua, A-Ke-Su Su-Jie, Zhou Yan-Nan, Gao Feng, Zheng Ai-Hua, Zhang Tai-Ming, Hou Wen-Zhong, Wang Jian, Du Xiang, Zhu Xiong-Zeng

Abstract excerpt

AIM: To investigate the significance of c-kit gene mutation in gastrointestinal stromal tumors (GIST). METHODS: Fifty two cases of GIST and 28 cases of other tumors were examined. DNA samples were extracted from paraffin sections and fresh blocks. Exons 11, 9 and 13 of the c-kit gene were amplified by PCR and sequenced. RESULTS: Mutations of exon 11 were found in 14 of 25 malignant GISTs (56%), mutations of exon...

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Identifiers

PMID: 15112348
DOI: 10.3748/wjg.v10.i9.1310
PMCID: PMC4622772

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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