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Article

Contributions of 18 additional DNA sequence variations in the gene encoding apolipoprotein E to explaining variation in quantitative measures of lipid metabolism.

American journal of human genetics - 1 Sept 2002

Stengård Jari H, Clark Andrew G, Weiss Kenneth M, Kardia Sharon, Nickerson Deborah A, Salomaa Veikko, Ehnholm Christian, Boerwinkle Eric, Sing Charles F

Abstract excerpt

Apolipoprotein E (ApoE) is a major constituent of many lipoprotein particles. Previous genetic studies have focused on six genotypes defined by three alleles, denoted epsilon2, epsilon3, and epsilon4, encoded by two variable exonic sites that segregate in most populations. We have reported studies of the distribution of alleles of 20 biallelic variable sites in the gene encoding the ApoE molecule within and among...

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Identifiers

PMID: 12165926
DOI: 10.1086/342217
PMCID: PMC449695

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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