Article
Apolipoprotein E polymorphism and cardiovascular disease: a HuGE review.
American journal of epidemiology - 15 Mar 2002
Eichner June E, Dunn S Terence, Perveen Ghazala, Thompson David M, Stewart Kenneth E, Stroehla Berrit C
Abstract excerpt
This review examines the association between the apolipoprotein (apo) var epsilon gene polymorphism (or its protein product (apo E)), metabolic regulation of cholesterol, and cardiovascular disease. The apo var epsilon gene is located at chromosome 19q13.2. Among the variants of this gene, alleles (*) epsilon2, (*) epsilon3, and (*) epsilon4 constitute the common polymorphism found in most populations. Of these...
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