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Article

Massive lymphocyte apoptosis in the thymus of functionally deficient TrkB mice.

Journal of neuroimmunology - 1 Aug 2002

Garcia-Suarez O, Blanco-Gelaz M A, Lopez M L, Germana A, Cabo R, Díaz-Esnal B, Silos-Santiago I, Ciriaco E, Vega J A

Abstract excerpt

The occurrence of TrkB in the murine thymus (15-day and 3-month old) was investigated by Northern blot, Western blot and immunohistochemistry. Furthermore, the thymus of 15-day-old mice carrying a non-functional mutation on trkB was analyzed. Both trkB mRNA and 145 kDa TrkB protein were detected. In addition, isolated lymphocytes and stromal cells also expressed this protein. The thymus of homozygous functionally...

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Source

Identifiers

PMID: 12161017
DOI: 10.1016/s0165-5728(02)00166-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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